hrp0097p1-295 | GH and IGFs | ESPE2023

Sex steroid priming decreases the frequency of divergent results between spontaneous and stimulated GH tests

Lennartsson Otto , Nilsson Ola , Lodefalk Maria

Introduction: The diagnosis of growth hormone (GH) deficiency (GHD) is complicated by the low specificity of GH testing, especially in children before and during early pubertal stages. Sex steroid priming reduces false positive results in pre- and early pubertal children. However, only a small number of studies have assessed its efficacy in improving the diagnostic accuracy of GHD investigations.Aim: To evaluate the effe...